Physicochemical characterization of experimental resin-based materials containing calcium orthophosphates or calcium silicate

Author(s)

Resende, Mariana C. A. ; Vilela, Handially S. ; Chiari, Marina D. S. ; Trinca, Rafael B. ; Silva, Flavia R. O. ; Braga, Roberto R.

• Document type: Journal article
• Source: Dental Materials; v. 40, n. 10, p. 8-pg., 2024-09-13.

Abstract

Objective: To evaluate experimental dimethacrylate-based materials containing calcium orthophosphates or calcium silicate particles in terms of their optical, mechanical and Ca2+ release behaviour. Methods: Dicalcium phosphate dihydrate (DCPD), hydroxyapatite (HAp), beta-tricalcium phosphate (beta-TCP) or calcium silicate (CaSi) particles were added to a photocurable BisGMA/TEGDMA resin (1:1 in mols) at a 30 vol% fraction. Materials containing silanized or non-silanized barium glass particles were used as controls. Degree of conversion (DC) at the top and base of 2-mm thick specimens was determined by ATR-FTIR spectroscopy (n = 5). Translucency parameter (TP) and transmittance (%T) were determined using a spectrophotometer (n = 3). Biaxial flexural strength (BFS) and flexural modulus (FM) were determined by biaxial flexural testing after 24 h storage in water (n = 10). Ca2+ release in water was determined during 28 days by inductively coupled plasma optical emission spectrometry (n = 3). Statistical analysis was performed using ANOVA/Tukey test (DC: two-way; TP, %T; BFS and FM: one-way; Ca2+ release: repeated measures two-way, alpha = 5 %). Results: CaSi and beta-TCP particles drastically reduced DC at 2 mm, TP and %T (p < 0.001). Compared to both controls, all Ca2+-releasing materials presented lower BFS (p < 0.001) and only the material with DCPD showed significantly lower FM (p < 0.05). The material containing CaSi presented the highest Ca2+ release, while among materials formulated with calcium orthophosphates the use of DCPD resulted in the highest release (p < 0.001). Significance: CaSi particles allowed the highest Ca2+ release. Notwithstanding, the use of DCPD resulted in a material with the best compromise between optical behaviour, DC, strength and Ca2+ release. (AU)

• FAPESP's process: 20/05986-5 - Development and application of calcium silicate nanoparticles for dental remineralization
• Grantee: Marina Damasceno e Souza de Carvalho Chiari
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/04737-4 - Dentin remineralization with the use of composite containing calcium orthophosphate particles associated with a Polymer-Induced Liquid Precursor (PILP): material development, in vitro and randomized clinical studies
• Grantee: Roberto Ruggiero Braga
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 20/12761-0 - In vitro analysis of dentin remineralization using glass ionomer cement with or without calcium orthophosphate particles or with mineral trioxide aggregate
• Grantee: Handially dos Santos Vilela
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 22/08411-9 - Effect of the addition of calcium silicate and calcium orthophosphate particles on the mechanical properties, optical properties and calcium release of experimental restorative composites
• Grantee: Mariana Carolayne Almeida Resende
• Support Opportunities: Scholarships in Brazil - Scientific Initiation