Photobiomodulation for oral mucositis management in pediatric patients: a systematic review

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Author(s):	Calarga, Caio Camargo ; Cotomacio, Claudia Carrara ; Simoes, Alyne Total Authors: 3
Document type:	Journal article
Source:	Lasers in Medical Science; v. 39, n. 1, p. 20-pg., 2024-11-10.
Abstract
This review aimed to determine whether photobiomodulation therapy (PBMT) is a safe and effective alternative for treating and preventing OM in children. The database search was carried out on PubMed, Embase, and Cochrane. Gray literature was also consulted through Google Scholar. Among 20 studies included, no adverse effect was reported, and only one study did not show any evidence of benefit from the use of PBMT. The analgesic effect of PBMT was emphasized and its action in accelerating the healing process and reducing the severity, duration and even incidence of OM was also noted. Evidence was found to encourage the use of PBMT to treat OM in pediatric patients. Higher quality studies must be developed in order to clarify the PBMT prophylactic effect and the best protocols for each clinical situation.The protocol of this review was registered on PROSPERO (CRD42023418109). (AU)

FAPESP's process:	23/09645-6 - Dysbiosis in the oral cavity and its relationship with complications in pediatric oncology patients and patients undergoing invasive mechanical ventilation, with or without antimicrobial photodynamic therapy.
Grantee:	Alyne Simões Gonçalves
Support Opportunities:	Regular Research Grants