| Full text | |
| Author(s): |
Araujo-Motta, Luiza
;
Alves-Lima, Cicero
;
Zambotti-Vilella, Leonardo
;
Colepicolo, Pio
Total Authors: 4
|
| Document type: | Journal article |
| Source: | PHYCOLOGY; v. 3, n. 2, p. 15-pg., 2023-06-01. |
| Abstract | |
We report here the effects of cadmium on the metabolome of the macroalga Gracilaria caudata. The IC50 of 3 mg/L (12 mu M) was obtained after 48 hrs exposure and induced lower photosynthesis efficiency. Threshold concentrations determined by the Brazilian Environmental Council (CONAMA) in marine waters (0.04 mg/L) and effluent discharge (0.2 mg/L) were also tested, and the latter changed photosynthetic efficiency similarly to IC50. A total of 43 metabolites were identified, including monosaccharides, carboxylic acids, and amino acids. By an unsupervised PCA, we identified significative alterations in the metabolome by the IC50. An OPLS-DA analysis showed that Cd2+ exposure caused the variation of 20 metabolites, mainly glyoxylate-related, ascorbate, floridoside and proline. Five metabolic pathways altered by Cd2+ showed an accumulation of amino acids, carbon metabolism intermediates and antioxidant responses to Cd2+. We recommend a review of the toxicity parameters and methods that guide environmental policies on cadmium levels in Brazilian marine waters. (AU) | |
| FAPESP's process: | 18/10216-4 - Analysis of the biochemical effects of Brazilians red macroalgae species exposed to cadmium |
| Grantee: | Luiza de Araujo Motta |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 16/06931-4 - Biodiversity of marine algae and metabolites of economical impact |
| Grantee: | Pio Colepicolo Neto |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |