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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of creatine supplementation on measured glomerular filtration rate in postmenopausal women

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Author(s):
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Neves, Jr., Manoel [1] ; Gualano, Bruno [2, 1] ; Roschel, Hamilton [2, 1] ; Lima, Fernanda Rodrigues [1] ; de Sa-Pinto, Ana Lucia [1] ; Seguro, Antonio Carlos [3] ; Shimizu, Maria Heloisa [3] ; Sapienza, Marcelo Tatit [4] ; Fuller, Ricardo [1] ; Lancha, Jr., Antonio Herbert [2] ; Bonfa, Eloisa [1]
Total Authors: 11
Affiliation:
[1] Univ Sao Paulo, Sch Med, Div Rheumatol, BR-01246903 Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Phys Educ & Sport, BR-01246903 Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Div Nephrol, BR-01246903 Sao Paulo - Brazil
[4] Univ Sao Paulo, Sch Med, Div Nucl Med, BR-01246903 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: APPLIED PHYSIOLOGY NUTRITION AND METABOLISM; v. 36, n. 3, p. 419-422, JUN 2011.
Web of Science Citations: 14
Abstract

We aimed to investigate whether creatine supplementation affects the measured glomerular filtration rate in postmenopausal women (age, 58 +/- 3 years). Subjects were randomly assigned to receive either creatine (20 g(.)day(-1) for 1 week and 5 g(.)day(-1) thereafter) or a placebo. Kidney function was assessed at baseline and after 12 weeks. {[}(51)Cr] EDTA clearance remained unchanged (CR-PRE: 86.16 +/- 14.36 mL(.)min(-1) per 1.73 m(2), POST: 87.25 +/- 17.60 mL(.)min(-1) per 1.73 m(2); PL-PRE: 85.15 +/- 8.54 mL(.)min(-1) per 1.73 m(2), POST: 87.18 +/- 9.64 mL(.)min(-1) per 1.73 m(2); p = 0.81). Thus, we concluded that creatine supplementation does not affect glomerular filtration rate in postmenopausal women. (AU)