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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

An electronic pressure-meter nociception paw test for mice

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Author(s):
Verri Junior, Waldiceu A. ; Vivancos, G. G. ; Moreira, I. F. ; Reis, S. ; Parada, C. A. ; Cunha, Fernando Q. ; Ferreira, Sergio H. ; Cunha, Thiago. Mattar [8]
Total Authors: 8
Document type: Journal article
Source: Brazilian Journal of Medical and Biological Research; v. 37, n. 3, p. 401-407, Mar. 2004.
Field of knowledge: Biological Sciences - Pharmacology
Abstract

The aim of the present investigation was to describe and validate an electronic mechanical test for quantification of the intensity of inflammatory nociception in mice. The electronic pressure-meter test consists of inducing the animal hindpaw flexion reflex by poking the plantar region with a polypropylene pipette tip adapted to a hand-held force transducer. This method was compared to the classical von Frey filaments test in which pressure intensity is automatically recorded after the nociceptive hindpaw flexion reflex...(AU)