| Full text | |
| Author(s): Show less - |
Ferreira, Rui Seabra
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Mantovani, Cristina Kampus
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Ferreira, Ana Silvia Sartori Barraviera Seabra
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Nascimento, Laura de Oliveira
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Ferrari, Merari de Fatima Ramires
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Kawano, Daniel Fabio
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Massirer, Katlin Brauer
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Anhe, Gabriel Forato
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Anholon, Rosley
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Caricati, Celso Pereira
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Ortega, Luciane Meneguin
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Guilbert, Sarah
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Lambe, Teresa
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Oliveira-Filho, Jose Paes
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Clemens, Sue Ann Costa
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Barraviera, Benedito
Total Authors: 16
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| Document type: | Journal article |
| Source: | Journal of Venomous Animals and Toxins including Tropical Diseases; v. 31, p. 7-pg., 2025-05-23. |
| Abstract | |
Background: In the biomedical field, translational science is the process of applying basic scientific knowledge to advance clinical research through the creation of new drugs, devices, medical procedures, preventive measures, and diagnostic kits. The Covid-19 pandemic exposed a shortage ofprofessionals trained in translational research, essential for responding to global demands. To drive advancements, researchers must overcome the 'valley of death', a critical phase in clinical investigation. In response, CEVAP at S & atilde;o Paulo State University (UNESP), Botucatu, Brazil, has developed a strong 'knowledge industry' centered on Translational Science. As part of its research and innovation efforts, CEVAP has developed two biopharmaceuticals, the fibrin sealant and the apilic antivenom, which are currently in the final stage of development. In 2024, CEVAP began the first Brazilian Contract Development and Manufacturing Organization (CDMO) for developing and producing validated and qualified pilot-scale batches to generate clinical trial material. Case Presentation: The implementation of the optional undergraduate course in Translational Science marks a crucial step in strengthening the 'knowledge industry'. The program, developed in collaboration with S & atilde;o Paulo's three public universities (USP, UNESP, and UNICAMP), also involves an international partnership with the University of Oxford's Department of Pediatrics and the Oxford Research Group LATAM. The successful launch of this course underscores its importance in interdisciplinary education and institutional collaboration. By bridging gaps between research and application, the program equips professionals to meet the growing demand for expertise in translational science. Given the project's success, it will transition into a one-year 'Qualification in Translational Science', available to students enrolled in S & atilde;o Paulo state universities. Conclusion: The preparation of these professionals will be strategic for transforming basic research into products for health, saving lives, and combating future pandemics that will emerge around the world. (AU) | |
| FAPESP's process: | 14/50897-0 - INCT 2014: Open-acess Medicinal Chemistry Centre (OpenMedChem) |
| Grantee: | Katlin Brauer Massirer |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 21/11936-3 - Center for Translational Science and Biopharmaceutical Development |
| Grantee: | Benedito Barraviera |
| Support Opportunities: | Research Grants - Science Centers for Development |