| Full text | |
| Author(s): |
Araque Gelves, Dayanna Isabel
;
Andreoli de Souza, Giulia Cristina
;
Salvador, Marcos Jose
;
Diaz-Rodriguez, Alondra Maria
;
Campos-Avelar, Ixchel
;
de los Santos-villalobo, Sergio
Total Authors: 6
|
| Document type: | Journal article |
| Source: | JOURNAL OF PLANT GROWTH REGULATION; v. N/A, p. 28-pg., 2025-10-28. |
| Abstract | |
Bioactive compounds are molecules synthesized by living organisms that have beneficial effects on human health. Among them, secondary metabolites (SMs) are produced by plants in response to environmental interactions, acting as a defense against abiotic or biotic stress. Their synthesis is influenced by factors such as temperature, light, nutrient availability, and CO2, as well as by interactions with endophytic, mycorrhizal, and rhizospheric microorganisms. These plant-microorganism interactions can induce or enhance the production of SMs, including phenols, alkaloids, terpenoids, and phytohormones. Microorganisms not only activate specific metabolic pathways but can also share biosynthetic pathways or act as elicitors. Plants modulate their microbiome through environmental conditions and molecular signals, shaping microbial communities with key roles in growth, stress tolerance, and production of bioactive compounds. These associations represent a promising biotechnological strategy for sustainable pharmaceutical, agricultural, and environmental applications. This review further explores innovative biotechnological strategies such as co-cultivation systems, synthetic microbial communities (SynComs), omics-based approaches, and genetic engineering to optimize metabolite yield and functionality. Overall, it highlights the potential of harnessing plant-microbe interactions as a sustainable and scalable source of bioactive compounds, contributing to ecosystem resilience and biotechnological innovation. (AU) | |
| FAPESP's process: | 06/06079-4 - Search of antioxidants and antimicrobials in Gomphreneae tribe species |
| Grantee: | Marcos José Salvador |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 15/03726-8 - Integrated chemical and biological study in the search for bioactive substances in plants* and development of analytical procedures. *(Amaranthaceae, Gesneriaceae, Myrtaceae e Annonaceae) |
| Grantee: | Marcos José Salvador |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 21/09693-5 - Use of microbiome technologies and bioassays for the search for new bioactive compounds in plants and symbionts: implications for metabolic responses, molecular diversity and bioactivity |
| Grantee: | Marcos José Salvador |
| Support Opportunities: | BIOTA-FAPESP Program - Regular Research Grants |
| FAPESP's process: | 17/03598-5 - Preventive effect of Ilex paraguariensis preparations (chimarrão, terere and mate tea) against damages caused by chronic ethanol consumption: comparative analysis of preparation technology, chemical profile and evaluation of therapeutic effect and safety |
| Grantee: | Mariana Mesquita Fonseca |
| Support Opportunities: | Scholarships in Brazil - Doctorate |