| Full text | |
| Author(s): |
Castello, W. S.
[1]
;
Spera, M. B. M.
[1]
;
Gomes, A. F.
[1]
;
Gozzo, F. C.
[1]
;
Lustri, W. R.
[2]
;
Formiga, A. L. B.
[1]
;
Corbi, P. P.
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Estadual Campinas UNICAMP, Inst Quim, BR-13083970 Campinas, SP - Brazil
[2] Associacao Sao Bento de Ensino, Ctr Univ Araraquara UNIARA, BR-14801320 Araraquara, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Journal of Coordination Chemistry; v. 64, n. 2, p. 272-280, 2011. |
| Web of Science Citations: | 2 |
| Abstract | |
A new platinum(II) complex with methionine sulfoxide was synthesized and characterized by chemical and spectroscopic techniques. Elemental analyses, mass spectrometric measurements (electrospray ionization quadrupole time-of-flight mass spectrometry), and thermal analyses of the solid compound fit the composition {[}(C(5)H(10)NO(3)S)Pt(mu-Cl)(2)Pt(C(5)H(10)NO(3)S)]center dot 2.5H(2)O. Infrared spectroscopic data indicate coordination of the ligand to Pt(II) through the nitrogen of NH(2) and the sulfur of the S=O group. (1)H-(15)N nuclear magnetic resonance spectroscopic data confirm nitrogen coordination. Antibacterial activities were evaluated by antibiogram assays using the disc diffusion method. The platinum(II) complex showed antibacterial activity against Gram-negative Pseudomonas aeruginosa bacterial cells. (AU) | |
| FAPESP's process: | 06/55367-2 - Complexos metálicos de platina (II), platina (IV), paládio (II), ouro (I) e ouro (III) com aminoácidos e derivados: síntese, caracterização e aplicações farmacológicas |
| Grantee: | Pedro Paulo Corbi |
| Support Opportunities: | Research Grants - Young Investigators Grants |
| FAPESP's process: | 10/00534-7 - Metal complexes with methionine sulfoxide: synthesis, characterization and biological applications. |
| Grantee: | Wellington Seixas Castello |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |