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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

APF and Dentifrice Effect on Root Dentin Demineralization and Biofilm

Full text
Author(s):
Vale, G. C. [1] ; Tabchoury, C. P. M. [1] ; Del Bel Cury, A. A. [1] ; Tenuta, L. M. A. [1] ; ten Cate, J. M. [2] ; Cury, J. A. [1]
Total Authors: 6
Affiliation:
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Piracicaba, SP - Brazil
[2] Acad Ctr Dent Amsterdam ACTA, Amsterdam - Netherlands
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF DENTAL RESEARCH; v. 90, n. 1, p. 77-81, JAN 2011.
Web of Science Citations: 30
Abstract

Because dentin is more caries-susceptible than enamel, its demineralization may be more influenced by additional fluoride (F). We hypothesized that a combination of professional F, applied as acidulated phosphate F (APF), and use of 1100-ppm-F dentifrice would provide additional protection for dentin compared with 1100-ppm-F alone. Twelve adult volunteers wore palatal appliances containing root dentin slabs, which were subjected, during 4 experimental phases of 7 days each, to biofilm accumulation and sucrose exposure 8x/day. The volunteers were randomly assigned to the following treatments: placebo dentifrice (PD), 1100-ppm-F dentifrice (FD), APF + PD, and APF+FD. APF gel (1.23% F) was applied to the slabs once at the beginning of the experimental phase, and the dentifrices were used 3x/day. APF and FD increased F concentration in biofilm fluid and reduced root dentin demineralization, presenting an additive effect. Analysis of the data suggests that the combination of APF gel application and daily regular use of 1100-ppm-F dentifrice may provide additional protection against root caries compared with the dentifrice alone. (AU)

FAPESP's process: 05/03090-4 - Fluoride influence on acidogenicity, polysaccharide concentration and genotypic diversity of mutans group streptococci in dental biofilm detected by AP-PCR: an in-situ study
Grantee:Gláuber Campos Vale
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 08/11696-8 - Effect of application of acidulated phosphate fluoride and use of fluoridated dentifrice in demineralization of dentine exposed to a high cariogenic challenge
Grantee:Cinthia Pereira Machado Tabchoury
Support Opportunities: Regular Research Grants