| Full text | |
| Author(s): |
Bronzi Guimaraes, Fabio Augusto
[1]
;
de Oliveira-Cardoso, Erika Arantes
[1, 2]
;
Mastropietro, Ana Paula
[3]
;
Voltarelli, Julio Cesar
[4]
;
dos Santos, Manoel Antonio
[5]
Total Authors: 5
|
| Affiliation: | [1] Univ Sao Paulo, Dept Psicol & Educ, Fac Filosofia Ciencias & Letras, BR-14040901 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Sch Med Ribeirao Preto, Clin Hosp, Bone Marrow Transplant Unit, Postgrad Program Psychol, Fac Philosophy Sci & Let, BR-14040901 Ribeirao Preto - Brazil
[3] Clin Hosp, Sch Med Ribeirao Preto, Occupat Therapy Serv, Postgrad Program Psychol, Ribeirao Preto - Brazil
[4] Clin Hosp, Sch Med Ribeirao Preto, Bone Marrow Transplant Unit, Ribeirao Preto - Brazil
[5] Univ Sao Paulo, Inst Psychol, Postgraduat Program Psychol, BR-14040901 Ribeirao Preto, SP - Brazil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Arquivos de Neuro-Psiquiatria; v. 68, n. 4, p. 522-527, AUG 2010. |
| Web of Science Citations: | 8 |
| Abstract | |
OBJECTIVE: To evaluate the impact of autologous hematopoetic stem cell transplantation (autoHSCT) in the health related quality of life (HRQL) in patients with multiple sclerosis. METHOD: The sample consisted of 34 patients, over 18 years old, treated at a University Hospital in the state of São Paulo, Brazil. For data collection MOS SF-36 and EDSS scales were applied at three time points: admission of the patient, hospital discharge and 1 year posttransplantation. RESULTS: 27 patients (79%) showed stabilization or neurological improvement 1 year posttransplantation. At this time point, there was statistically significant improvement in all domains of the HRQoL. When EDSS scores were correlated with the domains of the MOS SF-36 scale, statistically significant correlations were found with physical functioning at the three time points analysed. CONCLUSION: In spite of the high risk of complications of the procedure, the HSCT had positive impact in the health related quality of life. (AU) | |