Absence of ocular interaction in flicker ERG responses reflecting cone opponent and luminance signals

Author(s)

Salgueiro Barboni, Mirella Telles ^{[1, 2, 3]} ; Ventura, Dora Fix ^{[2, 3]} ; Kremers, Jan ^{[1, 4]}

Affiliation

^[1] Univ Hosp Erlangen, Dept Ophthalmol, Erlangen - Germany

^[2] Univ Sao Paulo, Dept Expt Psychol, Sao Paulo - Brazil

^[3] Univ Sao Paulo, Ctr Neurosci & Behav, Sao Paulo - Brazil

^[4] Univ Erlangen Nurnberg, Dept Ophthalmol, D-91054 Erlangen - Germany

• Document type: Journal article
• Source: DOCUMENTA OPHTHALMOLOGICA; v. 121, n. 1, p. 69-75, AUG 2010.
• Web of Science Citations: 4

Abstract

The aim of the study was to investigate whether there is an ocular interaction in the flicker ERG responses reflecting luminance and cone opponency in normal human subjects. Flicker ERGs were recorded from one dilated eye of 10 healthy volunteers. Each subject was tested twice: once with and once without occluding the opposite eye. Red and green LEDs were modulated in counterphase in a Ganzfeld stimulator. ERG responses were recorded for different ratios of the modulation in the red and green LEDs and at 12 and 36 Hz. The amplitudes and phases of the fundamental components were compared between the conditions with and without occlusion. The 12-Hz flicker ERGs reflected activity of the cone opponent channel, whereas the 36-Hz data reflected luminance activity. There were no significant differences between the conditions with and without occluding the opposite eye for any of the stimulus protocols. Ocular interaction is absent in flicker ERGs reflecting cone opponent and luminance activity. (AU)

• FAPESP's process: 07/55125-1 - Electrophysiological and psychophysical evaluation of ON and OFF visual pathways in Duchenne muscular dystrophy young patients
• Grantee: Mirella Telles Salgueiro Barboni
• Support Opportunities: Scholarships in Brazil - Doctorate