Antimicrobial activity from endophytic fungi Arthrinium state of Apiospora montagnei Sacc. and Papulaspora immersa

Author(s)

Ramos, Henrique Pereira ^[1] ; Braun, Glaucia Hollander ^[1] ; Pupo, Monica Tallarico ^[1] ; Said, Suraia ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Ciencias Farmaceut, BR-14040903 Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: Brazilian Archives of Biology and Technology; v. 53, n. 3, p. 629-632, MAY-JUN 2010.
• Web of Science Citations: 14

Abstract

Papulaspora immersa and Arthrinium state of Apiospora montagnei Sacc. were isolated from the roots of Smallanthus sonchifolius (yacón). The crude extracts from their cultures inhibited the growth of Staphylococcus aureus, Kocuria rhizophila, Pseudomonas aeruginosa and Escherichia coli. The more relevant results were observed in the ethyl acetate extract from P immersa against P aeruginosa (90 µg/mL) and ethyl acetate extract from Arthrinium state of A montagnei Sacc. against P aeruginosa (160 µg/mL). The two endophytic fungi isolated from yacón roots as well as their antimicrobial activity detected in the crude extracts cultures were being reported for the first time. (AU)

• FAPESP's process: 05/58427-3 - Optimization of the cultivation conditions of endophytic VA 16 for production of secondary metabolites with biological activities
• Grantee: Henrique Pereira Ramos
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 05/58426-7 - Optimization of the cultivation conditions of endophytic fungus VA 27 for production of bioactive substances
• Grantee: Glaucia Hollaender Braun
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 04/07935-6 - Bioprospection in fungi: the search of lead compounds for drug design and enzymes for pharmaceutical and industrial applications
• Grantee: Jairo Kenupp Bastos
• Support Opportunities: BIOTA-FAPESP Program - Thematic Grants