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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Expression of genes related to muscle plasticity after strength and power training regimens

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Author(s):
Lamas, L. [1] ; Aoki, M. S. [2] ; Ugrinowitsch, C. [1] ; Campos, G. E. R. [3] ; Regazzini, M. [1] ; Moriscot, A. S. [4] ; Tricoli, V. [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Sch Phys Educ & Sport, BR-05508030 Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Arts Sci & Humanities, BR-05508030 Sao Paulo - Brazil
[3] Univ Estadual Campinas, Inst Biol, Campinas, SP - Brazil
[4] Univ Sao Paulo, Inst Biomed Sci, BR-05508030 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS; v. 20, n. 2, p. 216-225, APR 2010.
Web of Science Citations: 21
Abstract

The purpose of our study was to compare the effects of 8-week progressive strength and power training regimens on strength gains and muscle plasticity {[}muscle fiber hypertrophy and phenotype shift, mammalian target of rapamycin (mTOR), regulatory-associated protein of mTOR (RAPTOR), rapamycin-insensitive companion of m-TOR (RICTOR), calcineurin and calcipressin gene expression]. Twenty-nine physically active subjects were divided into three groups: strength training (ST), power training (PT) and control (C). Squat 1 RM and muscle biopsies were obtained before and after the training period. Strength increased similarly for both ST and PT groups (P < 0.001). Fiber types I, IIa and IIb presented hypertrophy main time effect (P < 0.05). Only type IIb percentage decreased from pre- to post-test (main time effect, P < 0.05). mTOR and RICTOR mRNA expression increased similarly from pre- to post-test (P < 0.01). RAPTOR increased after training for both groups (P < 0.0001), but to a greater extent in the ST (P < 0.001) than in the PT group. 4EBP-1 decreased after training when the ST and PT groups were pooled (P < 0.05). Calcineurin levels did not change after training, while calcipressin increased similarly from pre- to post-test (P < 0.01). In conclusion, our data indicate that these training regimens produce similar performance improvements; however, there was a trend toward greater hypertrophy-related gene expression and muscle fiber hypertrophy in the ST group. (AU)

FAPESP's process: 06/00302-3 - Strength training with vibration: analysis of the determinant factors of vertical jump performance improvement
Grantee:Carlos Ugrinowitsch
Support Opportunities: Regular Research Grants