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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Toxoplasma gondii: host-parasite interaction and behavior manipulation

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Author(s):
da Silva, Rodrigo Costa [1] ; Langoni, Helio [1]
Total Authors: 2
Affiliation:
[1] Sao Paulo State Univ UNESP, Coll Vet Med & Anim Sci FMVZ, Dept Vet Hyg & Anim Sci DHVSP, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Review article
Source: Parasitology Research; v. 105, n. 4, p. 893-898, OCT 2009.
Web of Science Citations: 48
Abstract

Toxoplasma gondii is an obligate intracellular parasite that causes different lesions in men and other warm-blooded animals. Humoral and cellular immune response of the host against the parasite keeps the protozoan in a latent stage, and clinical disease ensues when immunological response is compromised. Brain parasitism benefits the parasite causing behavioral changes in the host, not only in animals but also in humans. Schizophrenia and epilepsy are two neurological disorders that have recently been reported to affect humans coinfected with T. gondii. Further studies based on host-parasite interaction in several wild or domestic warm-blooded species are still necessary in order to better understand parasitism and behavioral changes caused by T. gondii. (AU)

FAPESP's process: 06/07198-7 - Genotyping of Toxoplasma gondii samples isolated of ovines from slaughterhouse
Grantee:Helio Langoni
Support Opportunities: Regular Research Grants
FAPESP's process: 06/02486-4 - Genotypic characterization of Toxoplasma gondii samples isolated from slaughterhouse ovines
Grantee:Rodrigo Costa da Silva
Support Opportunities: Scholarships in Brazil - Doctorate