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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles

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Author(s):
Silva, F. A. N. [1, 2, 3] ; Galluzzi, M. P. [2] ; Albuquerque, B. [2] ; Pizzuti, L. [2] ; Gressler, V. [3] ; Rivelli, D. P. [1] ; Barros, S. B. M. [1] ; Pereira, C. M. P. [4, 2, 3, 5]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Pathol Lab, Dept Anal Clin & Toxicol, Fac Ciencias Farmaceut, BR-05508300 Sao Paulo - Brazil
[2] Univ Sao Paulo, Ctr Capacitacao & Pesquisa Meio Ambiente CEPEMA, BR-11573000 Cubatao, SP - Brazil
[3] Univ Sao Paulo, Lab Anal Toxicol, Dept Anal Clin & Toxicol, Fac Ciencias Farmaceut, BR-05508300 Sao Paulo - Brazil
[4] Univ Sao Paulo, Inst Quim, BR-05513970 Sao Paulo - Brazil
[5] Univ Fed Pelotas, Dept Quim Geociencias, BR-96010900 Pelotas, RS - Brazil
Total Affiliations: 5
Document type: Journal article
Source: LETTERS IN DRUG DESIGN & DISCOVERY; v. 6, n. 5, p. 323-326, JUL 2009.
Web of Science Citations: 15
Abstract

The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox(R). (AU)