Serologic Detection of Coccidioidomycosis Antibodies in Northeast Brazil

Author(s)

Cordeiro, Rossana de Aguiar ^{[1, 2]} ; Bezerra Fechine, Maria Auxiliadora ^[1] ; Nogueira Brilhante, Raimunda Samia ^[1] ; Gadelha Rocha, Marcos Fabio ^{[3, 1]} ; Freire da Costa, Ana Karoline ^{[3, 1]} ; Tiemi Dias Nagao, Maria Aparecida ^[4] ; de Camargo, Zoilo Pires ^[5] ; Costa Sidrim, Jose Julio ^[1]

Affiliation

^[1] Univ Fed Ceara, Specialized Med Mycol Ctr, Fortaleza, Ceara - Brazil

^[2] Univ Estadual Ceara, Dept Biol Sci, Fortaleza, Ceara - Brazil

^[3] Univ Estadual Ceara, Postgrad Program Vet Sci, Fortaleza, Ceara - Brazil

^[4] Univ Fed Ceara, Dept Clin & Toxicol Anal, Fortaleza, Ceara - Brazil

^[5] Univ Fed Sao Paulo, Dept Microbiol Immunol & Parasitol, Sao Paulo - Brazil

• Document type: Journal article
• Source: Mycopathologia; v. 167, n. 4, p. 187-190, APR 2009.
• Web of Science Citations: 6

Abstract

Coccidioidomycosis is a systemic infection caused by Coccidioides spp. The disease is endemic in Brazil but its incidence is underreported as it is not a notifiable disease. This article presents the results of a serologic survey carried out with 229 volunteers in northeast Brazil by the immunodiffusion (ID) test with commercial Coccidioides spp. antigens. The commercial ID test detected 15 individuals without clinical diagnosis of the disease and two individuals in treatment for coccidioidomycosis. Regarding the epidemiological data, most of the positive individuals were male, between 18 and 65 years of age and were engaged in armadillo hunting. Three women who had never participated in armadillo hunts also displayed positive results for coccidioidal antibodies. Besides armadillo hunts, exposure to environmental dust in endemic areas may account for the serologic response detected in the study. The data from this study suggest the importance of performing epidemiological surveys for coccidioidomycosis in order to understand the prevalence of this disease in Brazil. (AU)

• FAPESP's process: 04/14270-0 - Emergent fungal pathogens: epidemiology and diagnosis
• Grantee: Zoilo Pires de Camargo
• Support Opportunities: Research Projects - Thematic Grants