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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Improved catalysis of Morita-Baylis-Hillman reaction. The strong synergic effect using both an imidazolic ionic liquid and a temperature

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Author(s):
Porto, Ricardo S. [1] ; Amarante, Giovanni W. [1] ; Cavallaro, Mayra [1] ; Poppi, Ronei J. [2] ; Coelho, Fernando [1]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Inst Chem, Lab Synth Nat Prod & Drugs, BR-13084971 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Inst Chem, Lab Chemometr Analyt Chem, BR-13084971 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Tetrahedron Letters; v. 50, n. 11, p. 1184-1187, MAR 18 2009.
Web of Science Citations: 22
Abstract

The effect of different catalytic conditions for the Morita-Baylis-Hillman reaction has been evaluated both experimentally and by chemometry. The use of either ultrasound at 0 degrees C, ultrasound with an imidazolic ionic liquid at 0 degrees C or the ionic liquid catalyst at 0 and 50 degrees C was systematically tested. A strong synergic effect, which significantly increases the reaction rates and yields, was observed when the reactions were performed using an imidazolic ionic liquid catalyst at both 0 and 50 degrees C. (C) 2008 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 06/06347-9 - Synthesis of Drugs and bioactive substances from Morita-Baylis-Hillman adducts
Grantee:Fernando Antonio Santos Coelho
Support Opportunities: Regular Research Grants
FAPESP's process: 05/02373-2 - Synthesis of drugs and bioactive substances from Baylis-Hillman adducts: 1) synthesis of 4-fluoroquinolonic acid class antibiotics; 2) asymmetric synthesis of antiinflammatory DFP
Grantee:Giovanni Wilson Amarante
Support Opportunities: Scholarships in Brazil - Doctorate