A Fragmentation study of di-acidic mycosporine-like amino acids in electrospray and nanospray mass spectrometry

Author(s)

Cardozo, Karina H. M. ^{[1, 2]} ; Vessecchi, Ricardo ^[3] ; Galembeck, Sergio E. ^[3] ; Guaratini, Thais ^{[1, 2]} ; Gates, Paul J. ^[1] ; Pinto, Ernani ^[4] ; Lopes, Norberto P. ^[5] ; Colepicolo, Pio ^[2]

Affiliation

^[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon - England

^[2] Univ Sao Paulo, Inst Quim Sao Paulo, BR-05508900 Sao Paulo - Brazil

^[3] Univ Sao Paulo, Dept Quim, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto - Brazil

^[4] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Anal Clin & Toxicol, BR-05508900 Sao Paulo - Brazil

^[5] Univ Sao Paulo, Dept Quim & Fis, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: Journal of the Brazilian Chemical Society; v. 20, n. 9, p. 1625-1631, 2009.
• Web of Science Citations: 12

Abstract

Two mycosporine (MAAs), containing an extra acid function, were analyzed by nanospray and electrospray ionization tandem mass spectrometry. In contrast to the previous studies it is demonstrated that no significant characteristic methyl radical loss occurred in positive mode. The fragmentation pathway in negative mode was also proposed in this work, along with theoretical calculations to characterize the site of protonation. (AU)

• FAPESP's process: 01/13482-6 - Aspects of biochemical adaptation to the stress of pollutants in micro and macro seaweeds: modulation of cellular antioxidants and expression of defence proteins
• Grantee: Pio Colepicolo Neto
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 05/01572-1 - The use of computational chemistry in chemical processes involved in electrospray ionization
• Grantee: Ricardo Vessecchi Lourenço
• Support Opportunities: Scholarships in Brazil - Doctorate