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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Heck arylation of styrenes with arenediazonium salts: short, efficient, and stereoselective synthesis of resveratrol, DMU-212, and analogues

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Author(s):
Moro, Angelica Venturini [1] ; Cardoso, Flavio Sega P. [1] ; Correia, Carlos Roque D. [1]
Total Authors: 3
Affiliation:
[1] Univ Estadual Campinas, Inst Quim, BR-13084971 Campinas, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Tetrahedron Letters; v. 49, n. 39, p. 5668-5671, SEP 22 2008.
Web of Science Citations: 54
Abstract

Short, efficient, and stereoselective synthesis of the trans-stilbenes resveratrol, DMU-212, and analogues of both compounds are described. The synthesis of these important anti-cancer agents feature the palladium catalyzed Heck-Matsuda arylation of styrenes with arenediazonium tetrafluoroborates. (C) 2008 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 05/00721-3 - Exploring reliable methodologies for the synthesis of compounds of medicinal importance: total synthesis of novel neuroexcitatory aminoacids, of antitumor lactones, of the antidepressant paroxetin, and of new analogues of sphingosine and cerebrosides
Grantee:Carlos Roque Duarte Correia
Support Opportunities: Regular Research Grants