| Full text | |
| Author(s): |
Moro de Sousa, Ricardo Luiz
[1]
;
Moreli, Marcos Lazaro
[2]
;
Borges, Alessandra Abel
[2]
;
Campos, Gelse Mazzoni
[2]
;
Livonesi, Marcia Cristina
[2]
;
Moraes Figueiredo, Luiz Tadeu
[2]
;
Pinto, Aramis Augusto
[3]
Total Authors: 7
|
| Affiliation: | [1] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos, Dept Ciencias Basicas, Sch Zootech & Food Engn, BR-13635900 Pirassununga, SP - Brazil
[2] Univ Sao Paulo, Sch Med Ribeirao Preto, Ctr Res Virol, BR-14049 Ribeirao Preto, SP - Brazil
[3] Sao Paulo State Univ UNESP, Sch Vet & Agr Sci, Dept Vet Pathol, Jaboticabal, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Intervirology; v. 51, n. 4, p. 299-310, 2008. |
| Web of Science Citations: | 10 |
| Abstract | |
Objective: Hantaviruses are rodent-borne RNA viruses that have caused hantavirus cardiopulmonary syndrome in several Brazilian regions. In the present study, geographical distribution, seroprevalence, natural host range, and phylogenetic relations of rodent-associated hantaviruses collected from seven counties of Southeastern Brazil were evaluated. Methods: ELISA, RT-PCR and phylogenetic analysis were used in this study. Results: Antibodies to hantavirus were detected in Bolomys lasiurus, Akodon sp. and Oligoryzomys sp., performing an overall seroprevalence of 5.17%. All seropositive rodents were associated with grasslands or woods surrounded by sugar cane fields. Phylogenetic analysis of partial S- and M-segment sequences showed that viral sequences isolated from B. lasiurus specimens clustered with Araraquara virus. However, a sequence from Akodon sp. shared 100% similarity with Argentinian/Chilean viruses based on the partial S- segment amino acid sequence. Conclusion: These results indicate that there are associations between rodent reservoirs and hantaviruses in some regions of Southeastern Brazil, and suggest the existence of additional hantavirus genetic diversity and host ecology in these areas. Copyright (C) 2008 S. Karger AG, Basel (AU) | |
| FAPESP's process: | 01/01044-4 - Desenvolvimento e aplicação de métodos imunoenzimáticos e moleculares para a detecção e caracterização de hantavírus e arenavírus e da resposta imune humoral associada em roedores na região nordeste do estado de São Paulo |
| Grantee: | Ricardo Luiz Moro de Sousa |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 00/12638-0 - Detecção diagnóstica do genoma de Hantavírus brasileiros com sequenciamento nucleotídico para o estudo filogenético e clonagem com expressão de proteínas virais visando a produzir antígenos recombinantes |
| Grantee: | Marcos Lázaro Moreli |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 98/16497-0 - Estudo sobre os Hantavírus na região Nordeste do estado de São Paulo |
| Grantee: | Luiz Tadeu Moraes Figueiredo |
| Support Opportunities: | Regular Research Grants |