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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Leucine supplementation combined with resistance exercise improves the plasma lipid profile of dexamethasone-treated rats

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Author(s):
Nicastro, Humberto [1] ; da Luz, Claudia R. [1] ; Chaves, Daniela F. S. [1] ; das Neves, William [1] ; Valente, Kerolyn S. [1] ; Lancha, Jr., Antonio H. [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Lab Appl Nutr & Metab, Phys Educ & Sports Sch, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: LIPIDS IN HEALTH AND DISEASE; v. 11, JAN 11 2012.
Web of Science Citations: 2
Abstract

The impact of leucine supplementation and resistance exercise (RE) on plasma lipid profile was evaluated in adult rats treated with dexamethasone, an experimental model of dyslipidemia. Total cholesterol did not differ among groups. Furthermore, leucine supplementation did not promote improvement in the plasma total cholesterol and LDL-c of the animals. However, plasma TG and VLDL-c were significantly decreased and HDL-c increased after 7 days of leucine supplementation combined with RE. In conclusion, leucine supplementation combined with RE, but not isolated, improved the plasma lipid profile of dexamethasone-induced dyslipidemic rats. (AU)

FAPESP's process: 10/07062-3 - Leucine and skeletal muscle disuse: clinical anti-atrophic efficacy and related mechanisms
Grantee:Humberto Nicastro Silva
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 11/04690-6 - Effects of leucine and branched-chaim amino acids supplementation on resistance exercise-induced muscle damage and inflammation: a randomized, double-blind, and placebo-controlled study
Grantee:Claudia Ribeiro da Luz
Support Opportunities: Scholarships in Brazil - Master