The erosion and abrasion-inhibiting effect of TiF4 and NaF varnishes and solutions on enamel in vitro

Author(s)

Levy, Flavia Mauad ^[1] ; Magalhaes, Ana Carolina ^[1] ; Gomes, Marina Franciscon ^[1] ; Comar, Livia Picchi ^[1] ; Rios, Daniela ^[2] ; Rabelo Buzalaf, Marilia Afonso ^[1]

Affiliation

^[1] Univ Sao Paulo, Dept Biol Sci, Bauru Sch Dent, Bauru, SP - Brazil

^[2] Univ Sao Paulo, Dept Pediat Dent Orthodont & Publ Hlth, Bauru Sch Dent, Bauru, SP - Brazil

• Document type: Journal article
• Source: International Journal of Paediatric Dentistry; v. 22, n. 1, p. 11-16, JAN 2012.
• Web of Science Citations: 23

Abstract

Objective. Previous in vitro study has shown that TiF(4) varnish might reduce enamel erosion. No data regarding the effect of this experimental varnish on enamel erosion plus abrasion, however, are available so far. Thus, this in vitro study aimed to analyse the effect of TiF4 compared with NaF varnishes and solutions, to protect against enamel erosion with or without abrasion. Methods. Enamel specimens were pre-treated with experimental-TiF4 (2.45% F), experimentalNaF (2.45% F), NaF-Duraphat (2.26% F), and placebo varnishes; NaF (2.26% F) and TiF4 (2.45% F) solutions. Controls remained untreated. The erosive challenge was performed using a soft drink (pH 2.6) 4 u 90 s / day (ERO) and the toothbrushing abrasion (ERO+ ABR) 2 u 10 s / day, for 5 days. Between the challenges, the specimens were exposed to artificial saliva. Enamel loss was measured profilometrically (lm). Results. Kruskal-Wallis / Dunn tests showed that all fluoridated varnishes (TiF4-ERO: 0.53 +/- 0.20, ERO+ ABR: 0.65 +/- 0.19/ NaF-ERO: 0.94 +/- 0.18, ERO+ ABR: 1.74 +/- 0.37 / Duraphat-ERO: 1.00 +/- 0.37, ERO+ ABR: 1.72 +/- 0.58) were able to significantly reduce enamel loss when compared with placebo varnish (ERO: 3.45 +/- 0.41 / ERO+ ABR: 3.20 +/- 0.66) (P < 0.0001). Placebo varnish, control (ERO: 2.68 +/- 0.53 / ERO+ ABR: 3.01 +/- 0.34), and fluoridated (NaF-ERO: 2.84 +/- 0.09 / ERO+ ABR: 2.40 +/- 0.21 / TiF4-ERO: 3.55 +/- 0.59 / ERO+ ABR: 4.10 +/- 0.38) solutions did not significantly differ from each other. Conclusion. Based on the results, it can be concluded that the TiF4 varnish seems to be a promising treatment to reduce enamel loss under mild erosive and abrasive conditions in vitro. (AU)

• FAPESP's process: 08/07105-4 - Evaluation of the effect of an experimental TiF4 varnish compared to NaF varnishes and solutions and to TiF4 solution on erosion and abrasion of enamel and dentin: in vitro and in situ studies
• Grantee: Ana Carolina Magalhães
• Support Opportunities: Regular Research Grants
• FAPESP's process: 08/03727-0 - Evaluation of the effect of an experimental titanium tetrafluoride varnish compared to sodium fluoride varnishes and solutions on erosion and abrasion of enamel and dentin in vitro and in situ
• Grantee: Flavia Mauad Levy Abrahão
• Support Opportunities: Scholarships in Brazil - Post-Doctoral