| Full text | |
| Author(s): Show less - |
Anghinah, Renato
[1]
;
Medeiros Kanda, Paulo Afonso
[1]
;
Lopes, Helder Frederico
[1]
;
Hindi Basile, Luis Fernando
[1, 2]
;
Machado, Sergio
[3]
;
Ribeiro, Pedro.
[3]
;
Velasques, Bruna
[3]
;
Sameshima, Koichi
[4]
;
Takahashi, Daniel Yasumasa
[4]
;
Pinto, Lecio Figueira
[1]
;
Caramelli, Paulo
[5]
;
Nitrini, Ricardo
[1]
Total Authors: 12
|
| Affiliation: | [1] Univ Sao Paulo, Sch Med, Dept Neurol, Sao Paulo - Brazil
[2] Methodist Univ Sao Paulo UMESP, Psychophysiol Lab, Sao Paulo - Brazil
[3] Fed Univ Rio de Janeiro IPUB UFRJ, Inst Psychiat, Rio De Janeiro - Brazil
[4] Univ Sao Paulo, Sch Med, Dept Radiol, Sao Paulo - Brazil
[5] Univ Fed Minas Gerais, Fac Med, Dept Internal Med, Cognit & Behabioral Neurol Unit, Belo Horizonte, MG - Brazil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Arquivos de Neuro-Psiquiatria; v. 69, n. 6, p. 871-874, DEC 2011. |
| Web of Science Citations: | 9 |
| Abstract | |
There is evidence in electroencephalography that alpha, theta and delta band oscillations reflect cognitive and memory performances and that quantitative techniques can improve the electroencephalogram (EEG) sensitivity. This paper presents the results of comparative analysis of qEEG variables as reliable markers for Alzheimer's disease (AD). We compared the sensitivity and specificity between spectral analysis (spectA) and coherence (Coh) within the same group of AD patients. SpectA and Coh were calculated from EEGs of 40 patients with mild to moderate AD and 40 healthy elderly controls. The peak of spectA was smaller in the AD group than in controls. AD group showed predominance of slow spectA in theta and delta bands and a significant reduction of inter-hemispheric Coh for occipital alpha 2 and beta 1 and for frontal delta sub-band. ROC curve supported that alpha band spectA was more sensitive than coherence to differentiate controls from AD. (AU) | |
| FAPESP's process: | 02/13633-7 - Phospholipid metabolism in neuropsychiatric disorders |
| Grantee: | Wagner Farid Gattaz |
| Support Opportunities: | Research Projects - Thematic Grants |