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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bovine fetal DNA in the maternal circulation: Applications and implications

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Author(s):
Lemos, D. C. [1] ; Takeuchi, P. L. [1] ; Rios, A. F. L. [1, 2] ; Araujo, A. [1] ; Lemos, H. C. [1] ; Ramos, E. S. [1, 3]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Dept Genet, Fac Med Ribeirao Preto, BR-14049900 Ribeirao Preto, SP - Brazil
[2] Univ Estadual Norte Fluminense, Ctr Biociencias & Biotecnol, Campos Dos Goytacazes, RJ - Brazil
[3] Univ Sao Paulo, Dept Ginecol & Obstet, Fac Med Ribeirao Preto, BR-14049900 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Placenta; v. 32, n. 11, p. 912-913, NOV 2011.
Web of Science Citations: 13
Abstract

Objective: The main aim of the present study was to detect bovine fetal DNA in the maternal circulation, a relatively unexplored subject in the literature. Study design: DNA was extracted from blood of 84 primipara cows (Bos indicus) at different gestational ages (30-270 days) and from 100 adult animals (50 males and 50 non-pregnant cows). The samples were analyzed using PCR with primers for TSPY gene. Results: Molecular results matched the fetal phenotypic gender in all 47 male and 37 female fetuses, including early pregnancy, and in control animals. Conclusions: These results evidence a bovine transplacental fetal DNA passage. (C) 2011 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 09/08313-2 - Methylation pattern and differential MHM region expression during chicken gonadal development
Grantee:Ester Silveira Ramos
Support Opportunities: Regular Research Grants