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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Probiotic cheese attenuates exercise-induced immune suppression in Wistar rats

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Author(s):
Lollo, P. C. B. [1] ; Cruz, A. G. [1] ; Morato, P. N. [1] ; Moura, C. S. [1] ; Carvalho-Silva, L. B. [2] ; Oliveira, C. A. F. [3] ; Faria, J. A. F. [1] ; Amaya-Farfan, J. [1]
Total Authors: 8
Affiliation:
[1] Univ Estadual Campinas UNICAMP, FEA, BR-13083862 Sao Paulo - Brazil
[2] Univ Fed Alfenas UNIFENAS, Dept Nutr, BR-37130000 Alfenas, MG - Brazil
[3] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos Campus USP FZEA, BR-13635900 Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: JOURNAL OF DAIRY SCIENCE; v. 95, n. 7, p. 3549-3558, JUL 2012.
Web of Science Citations: 45
Abstract

Intense physical activity results in a substantial volume of stress and hence a significant probability of immunosuppression in athletes, with milk proteins being, perhaps, the most recommended protein supplements. Consumption of a probiotic cheese can attenuate immune suppression induced by exhausting exercise in rats. A popular Brazilian fresh cheese (Minas Frescal cheese) containing Lactobacillus acidophilus LA14 and Bifidobacterium longum BL05 was fed for 2 wk to adult Wistar rats, which then were brought to exhaustion on the treadmill. Two hours after exhaustion, the rats were killed and material was collected for the determination of serum uric acid, total and high-density lipoprotein cholesterol fraction, total protein, triacylglycerols, aspartate aminotransferase, alanine aminotransferase, creatine kinase, and blood cell (monocyte, lymphocyte, neutrophil, and leukocyte) counts. Exercise was efficient in reducing lymphocyte counts, irrespective of the type of ingested cheese, but the decrease in the group fed the probiotic cheese was 22% compared with 48% in the animals fed regular cheese. Monocyte counts were unaltered in the rats fed probiotic cheese compared with a significant decrease in the rats fed the regular cheese. Most importantly, ingestion of the probiotic cheese resulted in a >100% increase in serum high-density lipoprotein cholesterol and a 50% decrease in triacylglycerols. We conclude that probiotic Minas Reseal cheese may be a viable alternative to enhance the immune system and could be used to prevent infections, particularly those related to the physical overexertion of athletes. (AU)

FAPESP's process: 09/00059-0 - Milk whey proteins and leucine supplementation: influence on biochemical and body compositional parameters, and on the physical performance of exercising wistar rats
Grantee:Jaime Amaya Farfan
Support Opportunities: Regular Research Grants