Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Antimicrobial peptides: Clinical relevance and therapeutic implications

Full text
Author(s):
da Silva, Fabiano Pinheiro [1] ; Cesar Machado, Marcel Cerqueira [1]
Total Authors: 2
Affiliation:
[1] Univ Sao Paulo, Fac Med, Dept Emergency Med, Lab Emergencias Med, BR-01246903 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Review article
Source: Peptides; v. 36, n. 2, p. 308-314, AUG 2012.
Web of Science Citations: 79
Abstract

Antimicrobial peptides (AMPS) are molecules that provide protection against environmental pathogens, acting against a large number of microorganisms, including bacteria, fungi, yeast, virus and others. Two major groups of antimicrobial peptides are found in humans: cathelicidins and defensins. Recently, several studies have furnished information that besides their role in infection diseases, antimicrobial peptides play a role in diseases as diverse as inflammatory disorders, autoimmunity and cancer. Here, we discuss the role of antimicrobial peptides and vitamin D have in such complex diseases and propose their use should be more explored in the diagnosis and treatment of such conditions. (C) 2012 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 09/17731-2 - Markers of infection in critically ill patients
Grantee:Fabiano Pinheiro da Silva
Support Opportunities: Research Grants - Young Investigators Grants