Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis

Author(s)

Senhorinho, Gerusa N. A. ^[1] ; Nakano, Viviane ^[1] ; Liu, Chengxu ^[2] ; Song, Yuli ^[2] ; Finegold, Sydney M. ^{[2, 3, 4]} ; Avila-Campos, Mario J. ^[1]

Affiliation

^[1] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Anaerobe Lab, Sao Paulo - Brazil

^[2] VA Med Ctr W Los Angeles, Los Angeles, CA - USA

^[3] Univ Calif Los Angeles, Sch Med, Dept Med, Los Angeles, CA 90024 - USA

^[4] Univ Calif Los Angeles, Sch Med, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90024 - USA

• Document type: Journal article
• Source: Anaerobe; v. 18, n. 4, p. 381-385, AUG 2012.
• Web of Science Citations: 18

Abstract

The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis were identified 15 P. gulae, 12 F. nucleatum and 11 F. canifelinum. All strains were susceptible to most of the antibiotics tested, however, different resistance rates to clarithromycin, erythromycin and metronidazole among strains were observed. The role of P. gulae, P. macacae, F. nucleatum and F. canifelinum in periodontal disease of household pets needs to be defined to a better prevention and treatment of the canine periodontitis. (c) 2012 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 04/09077-7 - Microbiologic and molecular analyses of species of Porphyromonas and Prevotella isolated from humans and dogs with periodontal disease, and their relationship with the immunological response
• Grantee: Mario Júlio Ávila-Campos
• Support Opportunities: Regular Research Grants