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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Leptin: aspects on energetic balance, physical exercise and athletic amenorhea

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Author(s):
Sandra Maria Lima Ribeiro [1] ; Zirlene Adriana dos Santos [2] ; Renata Juliana da Silva [3] ; Eliana Louzada [4] ; José Donato Junior ; Julio Tirapegui [6]
Total Authors: 6
Affiliation:
[1] Universidade São Judas Tadeu. Programa de Pós Graduação Stricto Sensu em Educação Física. Grupo de Estudos em Nutrição e Atividade Física
[2] Universidade São Judas Tadeu. Programa de Pós Graduação Stricto Sensu em Educação Física. Grupo de Estudos em Nutrição e Atividade Física
[3] Universidade São Judas Tadeu. Programa de Pós Graduação Stricto Sensu em Educação Física. Grupo de Estudos em Nutrição e Atividade Física
[4] Universidade São Judas Tadeu. Programa de Pós Graduação Stricto Sensu em Educação Física. Grupo de Estudos em Nutrição e Atividade Física
[6] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Alimentos e Nutrição Experimental
Total Affiliations: 6
Document type: Journal article
Source: Arquivos Brasileiros de Endocrinologia e Metabologia; v. 51, n. 1, p. 11-24, 2007-02-00.
Abstract

The aim of this manuscript was to review the knowledge about leptin, detailing its relationship with energetic intake and physical activity. Leptin is an adipocyte hormone, recognized mainly for its putative role in control of energy expenditure, food intake, body weight and reproductive function. Leptin has still important peripheral actions, including its role on the ovarian tissue. The intracellular signaling mechanisms are recognized in hypothalamus, but in peripheral tissue are not fully understood. The exercise, when practiced by women, if not appropriately planned according to food intake, can modify the leptin release. When energy imbalances induced by exercise and/or deficient food ingestion occurs, low leptin levels are observed, leading to a reduction in GnRH (gonadotropin-release hormone), in LH (luteinizing hormone) and FSH (follicle-stimulating hormone) in pituitary, and consequently a minor release of ovarian estrogens. This process is named hypothalamic amenorrhea, and has repercussions in the woman's health. In this perspective, it is important to emphasize the need to evaluate the energy expenditure from exercise and to formulate adequate alimentary plans to these individuals. (AU)