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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Study of association between the ser-9-gly polymorphism of the D3 dopaminergic receptor and schizophrenia

Full text
Author(s):
Quirino Cordeiro Júnior [1] ; Ricardo Junqueira [2] ; Homero Vallada [3]
Total Authors: 3
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina. Hospital das Clínicas
[2] Universidade de São Paulo. Faculdade de Medicina. Departamento de Fisiopatologia Experimental
[3] Universidade de São Paulo. Faculdade de Medicina. Departamento de Psiquiatria
Total Affiliations: 3
Document type: Journal article
Source: Arquivos de Neuro-Psiquiatria; v. 59, p. 219-222, 2001-06-00.
Abstract

Two molecular genetic studies were undertaken to investigate the association between a ser-9-gly polymorphism in the dopamine D3 receptor gene and schizophrenia. The first study analysed 141 schizophrenic patients and 189 matched controls. In addition, an haplotype relative risk study was performed using 35 trios (mother, father, affected offspring). No allelic or genotype association was found in both studies. We conclude that this D3 polymorphism is not a risk factor for schizophrenia in our sample. (AU)

FAPESP's process: 97/11083-0 - Metabolism of phospholipids in schizophrenia and Alzheimer's disease
Grantee:Wagner Farid Gattaz
Support Opportunities: Research Projects - Thematic Grants