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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bacteriocin production by Bifidobacterium spp. A review

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Author(s):
Castillo Martinez, Fabio Andres [1] ; Balciunas, Eduardo Marcos [1] ; Converti, Attilio [2] ; Cotter, Paul D. [3, 4] ; de Souza Oliveira, Ricardo Pinheiro [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Biochem & Pharmaceut Technol Dept, BR-05508900 Sao Paulo - Brazil
[2] Univ Genoa, Dept Civil Chem & Environm Engn, I-16145 Genoa - Italy
[3] Teagasc Food Res Ctr, Fermoy, Cork - Ireland
[4] Alimentary Pharmabiot Ctr, Cork - Ireland
Total Affiliations: 4
Document type: Review article
Source: BIOTECHNOLOGY ADVANCES; v. 31, n. 4, p. 482-488, JUL-AUG 2013.
Web of Science Citations: 62
Abstract

Bacteriocins are ribosomally-synthesized antibacterial peptides. These compounds are produced by a broad variety of different bacteria belonging mainly to the genus Bifidobacterium, to which health promoting properties have frequently been attributed. However, despite the fact that the identification of Bifidobacterium-associated bacteriocins was first reported in 1980 and that they exhibit antimicrobial activity against pathogenic microorganisms such as Listeria monocytogenes, Clostridium perfringens, and Escherichia colt, relatively little information is still available about the antimicrobial compounds produced by strains of this genus. More detailed understanding of the action mechanisms of these antimicrobials could allow us to determine the extent to which their production contributes to the probiotic properties of specific bifidobacteria strains and, potentially, be of crucial significance for ultimate preservation of functional foods or pharmaceutical applications. Here we review what is already known about their structure, classification, mode of action, functionality, immunity, production and purification. (C) 2013 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 11/14048-0 - Production of bacteriocin by Bifidobacterium lactis using milk whey as a substrate
Grantee:Eduardo Marcos Balciunas
Support Opportunities: Scholarships in Brazil - Master