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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents

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Author(s):
Rizzo, Anapaula C. B. [1] ; Goldberg, Tamara B. L. [2] ; Silva, Carla C. [3] ; Kurokawa, Cilmery S. [4] ; Nunes, Helio R. C. [5] ; Corrente, Jose E. [6]
Total Authors: 6
Affiliation:
[1] Sao Paulo State Univ UNESP, Botucatu Sch Med, Dept Pediat, Sao Paulo - Brazil
[2] Sao Paulo State Univ UNESP, Botucatu Sch Med, Adolescent Med Course, Post Grad Program Gynecol Obstet & Mastol, Dept Pe, Sao Paulo - Brazil
[3] Univ North Parana, Dept Phys Educ, Curitiba, Parana - Brazil
[4] Sao Paulo State Univ UNESP, Botucatu Sch Med, Dept Pediat, Clin & Expt Pediat Res Ctr, Sao Paulo - Brazil
[5] Sao Paulo State Univ UNESP, Botucatu Sch Med, Sao Paulo - Brazil
[6] Sao Paulo State Univ UNESP, Botucatu Sch Med, Dept Stat, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: NUTRITION JOURNAL; v. 12, JAN 30 2013.
Web of Science Citations: 28
Abstract

Background: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population. Methods: A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI >= 85th percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI). Results and discussion: Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference >= 90th percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure >= 130/85 mm/Hg (21%), Triglycerides >= 150 mg/dL (18.5%), and Fasting Glycemia >= 100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents. Conclusion: An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females. (AU)

FAPESP's process: 11/05991-0 - The impact of body fat excess on bone densitometry and bone metabolims biomarkers: a study with overweight, obese and superobese adolescents
Grantee:Tamara Beres Lederer Goldberg
Support type: Regular Research Grants