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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Recent mouse and rat methods for the study of experimental oral candidiasis

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Author(s):
Costa, Anna C. B. P. [1] ; Pereira, Cristiane A. [1] ; Junqueira, Juliana C. [1] ; Jorge, Antonio O. C. [1]
Total Authors: 4
Affiliation:
[1] UNESP Univ Estadual Paulista, Dept Biosci & Oral Diagnosis, Inst Sci & Technol, Sao Jose Dos Campos - Brazil
Total Affiliations: 1
Document type: Journal article
Source: VIRULENCE; v. 4, n. 5, p. 391-399, JUL 1 2013.
Web of Science Citations: 17
Abstract

The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. Therefore, the study of experimentally induced oral candidiasis in rats and mice is useful to clarify the etiopathology of this condition, improve diagnosis, and search for new therapeutic options because the disease process in these animals is similar to that of human candidiasis lesions. Here, we describe and discuss new studies involving rat and mouse models of oral candidiasis with respect to methods for inducing experimental infection, methods for evaluating the development of experimental candidiasis, and new treatment strategies for oral candidiasis. (AU)

FAPESP's process: 10/00879-4 - OPPORTUNISTIC MICROORGANISMS IN INJURIES denture stomatitis AND INFLUENCE OF PHOTODYNAMIC THERAPY IN VIRULENCE FACTORS OF Candida spp.
Grantee:Cristiane Aparecida Pereira Correia
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 11/21346-7 - GENES WITH UNKNOWN FUNCTION OF Candida albicans AS TO BIOFILM FORMATION, BIOLOGICAL CHARACTERISTICS AND HOST- PATHOGEN INTERACTION
Grantee:Anna Carolina Borges Pereira da Costa
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 10/18753-7 - Evaluation of photodynamic therapy on Candida albicans in vitro and in vivo
Grantee:Antonio Olavo Cardoso Jorge
Support Opportunities: Regular Research Grants
FAPESP's process: 10/19117-7 - Effects of Cymbopogon citratus and Melaleuca alternifolia in the oral candidiasis in immunosuppressed mice
Grantee:Juliana Campos Junqueira
Support Opportunities: Regular Research Grants