Attentional and executive functions are differentially affected by post-traumatic stress disorder and trauma

Author(s)

Flaks, Mariana K. ^{[1, 2]} ; Malta, Stella M. ^[1] ; Almeida, Priscila P. ^[1] ; Bueno, Orlando F. A. ^[3] ; Pupo, Mariana C. ^[2] ; Andreoli, Sergio B. ^[4] ; Mello, Marcelo F. ; Lacerda, Acioly L. T. ^[1] ; Mari, Jair J. ^[1] ; Bressan, Rodrigo A. ^[1]

Affiliation

^[1] Univ Fed Selo Paulo UNIFESP, LiNC Lab Interdisciplinar Neurociencias C, Sao Paulo - Brazil

^[2] Univ Fed Selo Paulo UNIFESP, PROVE Programa Atendimento & Pesquisa Violencia, Sao Paulo - Brazil

^[3] Univ Fed Selo Paulo UNIFESP, Dept Psicobiol, Sao Paulo - Brazil

^[4] Univ Fed Selo Paulo UNIFESP, NEMAP Nucleo Estat & Metodol Aplicada, Sao Paulo - Brazil

• Document type: Journal article
• Source: JOURNAL OF PSYCHIATRIC RESEARCH; v. 48, n. 1, p. 32-39, JAN 2014.
• Web of Science Citations: 19

Abstract

Background: Among the neurocognitive impairments observed in patients with Post-traumatic Stress Disorder (PTSD), attentional and executive dysfunctions appear to correlate with negative effects on education, work, daily life activities, and social relations, as well as the re-experiencing, avoidance, and hyperarousal symptoms of PTSD. However, there is no consensus regarding which aspects of attentional and executive functions are impaired in PTSD patients. Methods: Attentional and executive functions were assessed using the digit span (WAIS-III) and spatial span (WMS-III) tests under forward and backward recall conditions, the Stroop Test, and the Wisconsin Card Sorting Test (WCST). Our sample was composed of victims of urban violence who developed PTSD (PTSD+) (n = 81), victims of urban violence who did not develop PTSD (PTSD) (n = 70), and healthy controls not exposed to trauma (HC) (n = 50). Results: The PTSD+ group had poorer performance on the spatial span forward subtest (p = 0.023; eta(2) = 0.038) and poorer execution time (p = 0.023; eta(2) = 0.042) and accuracy (p = 0.019; eta(2) = 0.044) on the Stroop Test compared to HC. Conclusions: These data suggest that there are few differences between the PTSD+ and HC groups, which are restricted to less complex measures of attentional and executive functional processes (short term capacity, selective attention, processing speed, and inhibitory control) and are related to visual stimuli. Therefore, cognitive impairments directly correlated with the manifestation of PTSD. (C) 2013 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 04/15039-0 - Post-traumatic stress disorder: epidemiology, physiopathology and treatment
• Grantee: Jair de Jesus Mari
• Support type: Research Projects - Thematic Grants
• FAPESP's process: 09/01358-0 - Neuropsychological study of factors related to the resilience and vulnerability to post-traumatic stress disorder
• Grantee: Mariana Kneese Flaks
• Support type: Scholarships in Brazil - Post-Doctorate