Antimicrobial activity of selected essential oils against cariogenic bacteria

Author(s)

Aguiar, G. P. ^[1] ; Carvalho, C. E. ^[1] ; Dias, H. J. ^[1] ; Reis, E. B. ^[1] ; Martins, M. H. G. ^[1] ; Wakabayashi, K. A. L. ^[1] ; Groppo, M. ^[2] ; Martins, C. H. G. ^[1] ; Cunha, W. R. ^[1] ; Crotti, A. E. M. ^[1]

Affiliation

^[1] Univ Franca, Nucleo Pesquisas Ciencias Exatas & Tecnol, Franca, SP - Brazil

^[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14049 Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: NATURAL PRODUCT RESEARCH; v. 27, n. 18, p. 1668-1672, SEP 1 2013.
• Web of Science Citations: 15

Abstract

The antibacterial activity of nine selected essential oils (EOs) against a panel of oral pathogens was investigated in terms of their minimum inhibitory concentrations (MICs) by using the broth microdilution method. Most of the EOs displayed weak activity or were inactive against the selected oral pathogens, with MIC values ranging from 500 to 4000g/mL. However, the EO obtained from the leaves of Bidens sulphurea (Asteraceae) was found to display moderate activity against Streptococcus mutans (MIC=250g/mL) and significant activity against Streptococcus mitis (MIC=31.25g/mL). Germacrene D (38.3%), trans-caryophyllene (18.0%), -elemene (13.9%) and bicyclogermacrene (13.1%) were identified as the main chemical components of this oil. 2,6-Di-tert-butyl-4-methylphenol, previously described as the major constituent in the EO from the flowers of B. sulphurea, was not detected in this study. (AU)

• FAPESP's process: 10/17443-4 - Evaluation of the antimicrobial and schistossomicidal potential of Bidens sulphurea (Cav.) Sch. Bip. (Asteraceae)
• Grantee: Gabriela de Paula Aguiar
• Support Opportunities: Scholarships in Brazil - Scientific Initiation