Cyclodextrin Inclusion Complexes Loaded in Particles as Drug Carrier Systems

Author(s)

Fraceto, Leonardo Fernandes ^{[1, 2]} ; Grillo, Renato ^{[1, 2]} ; Sobarzo-Sanchez, Eduardo ^[3]

Affiliation

^[1] Univ Estadual Campinas, Dept Bioquim, Campinas, SP - Brazil

^[2] Univ Estadual Paulista, UNESP, Dept Engn Ambiental, BR-18087180 Sorocaba, SP - Brazil

^[3] Univ Santiago de Compostela, Fac Pharm, Dept Pharm & Pharmaceut Technol, Santiago De Compostela - Spain

• Document type: Review article
• Source: CURRENT TOPICS IN MEDICINAL CHEMISTRY; v. 14, n. 4, p. 518-525, FEB 2014.
• Web of Science Citations: 17

Abstract

This mini-review paper does not consider classical work concerning the formation of inclusion complexes between pharmaceuticals and cyclodextrins. Instead, it highlights recent reports concerning the association of these host: guest systems with other carrier systems such as liposomes and nanoparticles showing the state of art of this subject with examples of developed systems and the advantages of these strategy in order to be potential systems as drug carriers. (AU)

• FAPESP's process: 11/01872-6 - Polymeric nanoparticles as delivery system for herbicides: preparation, characterization, interaction with humic substances and assessment of biological activity
• Grantee: Renato Grillo
• Support type: Scholarships in Brazil - Doctorate
• FAPESP's process: 09/00294-9 - Micro/nanostructured release systems for triazinic herbicides for agricultural application
• Grantee: Leonardo Fernandes Fraceto
• Support type: Research Grants - Young Investigators Grants