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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Septic arthritis: immunopathogenesis, experimental models and therapy

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Author(s):
Colavite, Priscila Maria [1] ; Sartori, Alexandrina [1]
Total Authors: 2
Affiliation:
[1] Univ Estadual Paulista, UNESP, Inst Biociencias, Dept Microbiol & Imunol, Botucatu, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Journal of Venomous Animals and Toxins including Tropical Diseases; v. 20, MAY 6 2014.
Web of Science Citations: 16
Abstract

Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included. (AU)

FAPESP's process: 11/04323-3 - Impact of the use of an immunomodulatory drug in the treatment of septic arthritis induced by Staphylococcus aureus
Grantee:Priscila Maria Colavite Machado
Support Opportunities: Scholarships in Brazil - Master