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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Efficacy of Papacarie (R) in reduction of residual bacteria in deciduous teeth: a randomized, controlled clinical trial

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Author(s):
Motta, Lara Jansiski [1] ; Bussadori, Sandra Kalil [1] ; Campanelli, Ana Paula [2] ; da Silva, Andre Luis [2] ; Alfaya, Thays Almeida [3] ; Leal de Godoy, Camila Haddad [1] ; de Lima Navarro, Maria Fidela [2]
Total Authors: 7
Affiliation:
[1] Univ Nove Julho, Sao Paulo - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Bauru, SP - Brazil
[3] Univ Fed Fluminense, Dent Clin, Postgrad Program, Sao Goncalo, RJ - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Clinics; v. 69, n. 5, p. 319-322, 2014.
Web of Science Citations: 9
Abstract

OBJECTIVES: The aim of the present study was to analyze the efficacy of Papacarie (R) gel compared with the traditional method (low-speed bur) in reducing the counts of total bacteria, Lactobacillus, total Streptococcus and Streptococcus mutans group. METHODS: A randomized, controlled clinical trial with a split-mouth design was performed. The sample comprised 40 deciduous teeth in 20 children (10 males and 10 females) aged four to seven years. The teeth were randomly allocated to two groups: G1, or chemomechanical caries removal with Papacarie Duo (R), and G2, or the removal of carious dentin tissue with a low-speed bur. Infected dentin was collected prior to the procedure, and the remaining dentin was collected immediately following the removal of the carious tissue. Initial and final counts of bacterial colonies were performed to determine whether there was a reduction in the number of colony-forming units (CFUs) of each microorganism studied. ClinicalTrials.gov:NCT01811420. RESULTS: Reductions were found in the numbers of total bacteria, total Streptococcus and Streptococcus mutans group following either of the caries removal methods (p < 0.05). A reduction was also noted in the number of Lactobacillus CFUs; however, this difference did not achieve statistical significance (p > 0.05). CONCLUSION: Papacarie (R) is an excellent option for the minimally invasive removal of carious tissue, achieving significant reductions in total bacteria, total Streptococcus and S. mutans with the same effectiveness as the traditional caries removal method. (AU)

FAPESP's process: 08/08642-3 - "RANDOMIZED CLINICAL TRIAL OF PAPACÁRIE" GEL IN THE CHEMICO-MECHANICAL REMOVAL OF CARIES LESION"
Grantee:Maria Fidela de Lima Navarro
Support Opportunities: Regular Research Grants