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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Test-Retest Reliability of fMRI Activation Generated by Different Saccade Tasks

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Author(s):
Lukasova, Katerina [1, 2] ; Sommer, Jens [3] ; Nucci-da-Silva, Mariana P. [1] ; Vieira, Gilson [1, 4] ; Blanke, Marius [5] ; Bremmer, Frank [5] ; Sato, Joao R. [6] ; Kircher, Tilo [3] ; Amaro, Jr., Edson [1]
Total Authors: 9
Affiliation:
[1] Univ Sao Paulo, Fac Med, NIF LIM44, BR-05403001 Sao Paulo - Brazil
[2] Univ Cruzeiro Sul, Fac Psychol, Sao Paulo - Brazil
[3] Univ Marburg, Dept Psychiat, Marburg - Germany
[4] Univ Sao Paulo, Bioinformat Grad Program, BR-05403001 Sao Paulo - Brazil
[5] Univ Marburg, Dept Neurophys, Marburg - Germany
[6] Univ Fed ABC, Ctr Math Computat & Cognit, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: Journal of Magnetic Resonance Imaging; v. 40, n. 1, p. 37-46, JUL 2014.
Web of Science Citations: 4
Abstract

Purpose: To assess the reproducibility of brain-activation and eye-movement patterns in a saccade paradigm when comparing subjects, tasks, and magnetic resonance (MR) systems. Materials and Methods: Forty-five healthy adults at two different sites (n = 45) performed saccade tasks with varying levels of target predictability: predictable (PRED), position predictable (pPRED), time predictable (tPRED), and prosaccade (SAC). Eye-movement pattern was tested with a repeated-measures analysis of variance. Activation maps reproducibility were estimated with the cluster overlap Jaccard index and signal variance coefficient of determination for within-subjects test-retest data, and for between-subjects data from the same and different sites. Results: In all groups latencies increased with decreasing target predictability: PRED < pPRED < tPRED < SAC (P < 0,001). Activation overlap was good to fair (>0.40) in all tasks in the within-subjects test-retest comparisons and poor (<0.40) in the tPRED for different subjects. The overlap of the different tasks for within-groups data was higher (0.40-0.68) than for the between-groups data (0.30-0.50). Activation consistency was 60-85% in the same subjects, 50-79% in different subjects, and 50-80% in different sites. In SAC, the activation found in the same and in different subjects was more consistent than in other tasks (50-80%). Conclusion: The predictive saccade tasks produced evidence for brain-activation and eye-movement reproducibility. (AU)

FAPESP's process: 05/56464-9 - Neuroscience Imaging Center at University of São Paulo Medical School
Grantee:Giovanni Guido Cerri
Support Opportunities: Inter-institutional Cooperation in Support of Brain Research (CINAPCE) - Thematic Grants