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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Phylogenetic characterization of feline immunodeficiency virus (FIV) isolates from the state of São Paulo

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Author(s):
Valéria M. Lara [1] ; Sueli A. Taniwaki [2] ; João P. Araújo Jr [3]
Total Authors: 3
Affiliation:
[1] Universidade Federal de Santa Maria. Centro de Ciências da Saúde. Departamento de Microbiologia e Parasitologia - Brasil
[2] Universidade Estadual Paulista. Instituto de Biociências. Departamento de Microbiologia e Imunologia - Brasil
[3] Universidade Estadual Paulista. Instituto de Biociências. Departamento de Microbiologia e Imunologia - Brasil
Total Affiliations: 3
Document type: Journal article
Source: Pesquisa Veterinária Brasileira; v. 27, n. 11, p. 467-470, 2007-11-00.
Abstract

Feline immunodeficiency virus (FIV) is a lentivirus associated with immunologic disorders in domestic cats. Due to the high genetic variability of FIV, five subtypes (A to E) have been identified and diversity within each subtype is also frequent. The study of the genetic diversity can aid the understanding the pathogenesis and epidemiology of the disease. Therefore, the present work aimed to analyze phylogenetically FIV isolates of domestic cats from the state of São Paulo, Brazil. The sequencing of 658 bp of the gag gene from 23 samples was performed and the results were analyzed using the Tamura-Nei nucleotidic substitution method. The phylogenetic analysis showed that all viruses belong to subtype B, and clearly three subgroups were present within this subtype. Additionally, these results suggest a common ancestor between the FIV strains derived from Japan and one Brazilian virus. In conclusion, this work presents the first information about the genetic diversity of FIV in the state of São Paulo. Additional studies are necessary to characterize the real scenario of the distribution of FIV subtypes in the population of Brazilian cats. (AU)