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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cytotoxicity and genotoxicity of carbon nanotubes

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Author(s):
Leonardo P. Franchi [1] ; Raquel A. Santos [2] ; Elaine Y. Matsubara [3] ; Juliana C. de Lima [4] ; J. Maurício Rosolen [5] ; Catarina S. Takahashi
Total Authors: 6
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética - Brasil
[2] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Genética - Brasil
[3] Universidade de São Paulo. Faculdade de Filosofia Ciências e Letras de Ribeirão Preto. Departamento de Química - Brasil
[4] Universidade de São Paulo. Faculdade de Filosofia Ciências e Letras de Ribeirão Preto. Departamento de Química - Brasil
[5] Universidade de São Paulo. Faculdade de Filosofia Ciências e Letras de Ribeirão Preto. Departamento de Química - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Química Nova; v. 35, n. 3, p. 571-580, 2012-00-00.
Abstract

There are many controversies regarding the cyto- and genotoxicity of carbon nanotubes (CNTs). In this work, we discuss that many of the incongruous arguments are probably associated with the poor physical-chemical characterization of the CNT samples used in many publications. This manuscript presents examples of carbon nanostructures observed under high resolution electron microscopy that can be found in typical CNT samples, and shows which roles in cyto- and genotoxicity need to be better investigated. Issues concerning chemical treatment are addressed and examples of misunderstandings that can occur during the studies of cyto- and genotoxicity of CNT samples are given. (AU)

FAPESP's process: 10/10863-8 - Cytotoxic and genotoxic effects of nanoparticles in cell lines in vitro.
Grantee:Leonardo Pereira Franchi
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 10/07681-5 - Development and study of micro/nanostructurated materials of interest for Lithium ion battery and capacitors
Grantee:Jose Mauricio Rosolen
Support Opportunities: Regular Research Grants