| Full text | |
| Author(s): |
Emília Kiyomi Kuroda
[1]
;
Alessandro Minillo
[2]
;
Odete Rocha
[3]
;
Edson Rodrigues Filho
[4]
;
Luiz Di Bernardo
[5]
Total Authors: 5
|
| Affiliation: | [1] Universidade de São Paulo. Escola de Engenharia de São Carlos. Departamento de Hidráulica e Saneamento
[2] Universidade de São Paulo. Escola de Engenharia de São Carlos. Departamento de Hidráulica e Saneamento
[3] Universidade Federal de São Carlos. Departamento de Ecologia e Biologia Evolutiva
[4] Universidade Federal de São Carlos. Departamento de Química
[5] Universidade de São Paulo. Escola de Engenharia de São Carlos. Departamento de Hidráulica e Saneamento
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Engenharia Sanitária e Ambiental; v. 12, n. 1, p. 24-31, 2007-03-00. |
| Abstract | |
This study was carried out to evaluate the toxicity of a strain of Microcystis spp, using acute toxicity bioassays with swiss albino mice and to characterize chemically the microcistins using high efficiency liquid chromatography with photodiode array detector (HPLC-PDA) and mass spectrometry with electrospray ionization (MS-ESI). The acute toxicity tests with mice showed that according to the classification proposed by Lawton et al (1994b), the toxic strain here tested corresponds to the degree of high toxicity with DL50 24h values for the dry extract lower than 100 mg/kg corporal weight (13,7 mg/kg corporal weight), while DL50(24h) for total microcystin - MCs concentration around 24,2 µg/kg corporal weight. and concentration of MCs in the dry material higher than 1,0 µg/mg dry weight (between 1.64 and 1.86 µg/mg d.w.). (AU) | |