Evaluation of residual antimicrobial activity of flumequine solutions subjected to electrochemical and photo-electrochemical processes

Author(s)

Caio Rodrigues-Silva ^[1] ; Milena G. Maniero ^[2] ; José Roberto Guimarães ^[3]

Affiliation

^[1] Universidade Estadual de Campinas. Faculdade de Engenharia Civil, Arquitetura e Urbanismo. Departamento de Saneamento e Ambiente - Brasil

^[2] Universidade Estadual de Campinas. Faculdade de Engenharia Civil, Arquitetura e Urbanismo. Departamento de Saneamento e Ambiente - Brasil

^[3] Universidade Estadual de Campinas. Faculdade de Engenharia Civil, Arquitetura e Urbanismo. Departamento de Saneamento e Ambiente - Brasil

• Document type: Journal article
• Source: Química Nova; v. 37, n. 5, p. 789-795, 2014-06-00.

Abstract

Flumequine degradation by electrochemical and photo-electrochemical processes was evaluated in this study. The antimicrobial activity of the solutions subjected to the electrochemical processes was monitored during the assays. The experiments were carried out using DSA® (dimensionally stable anode) electrode. The influence of current density was investigated for the 7.5 to 45 mA cm-2 range. The photo-electrochemical process was more efficient for degrading flumequine (85%) and reducing solution antimicrobial activity. For both processes, the residual antimicrobial activity decreased as flumequine degradation increased. The reaction intermediate m/z 244 (5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid) was identified. (AU)

• FAPESP's process: 08/06470-0 - DEGRADATION OF VETERINARY DRUGS
• Grantee: José Roberto Guimarães
• Support Opportunities: Regular Research Grants