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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Oral and cervical HPV infection in HIV-positive and HIV-negative women attending a sexual health clinic in Sao Paulo, Brazil

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Author(s):
Lima, Marina D. M. [1, 2] ; Braz-Silva, Paulo Henrique [1, 3] ; Pereira, Sonia M. [4] ; Riera, Catalina [5] ; Coelho, Ariane C. [6] ; Gallottini, Marina [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Sch Dent, Dept Stomatol, Sao Paulo - Brazil
[2] Univ Fed Piaui, Dept Pathol & Clin Dent, Teresina - Brazil
[3] Univ Sao Paulo, Inst Trop Med, Virol Lab, Sao Paulo - Brazil
[4] Adolfo Lutz Inst, Div Pathol, Sao Paulo - Brazil
[5] Ctr Sexually Transmitted Dis CRT DST AIDS SP, Div Dent, Sao Paulo - Brazil
[6] Ctr Sexually Transmitted Dis CRT DST AIDS SP, Div Gynecol, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: International Journal of Gynecology & Obstetrics; v. 126, n. 1, p. 33-36, JUL 2014.
Web of Science Citations: 8
Abstract

Objective: To investigate the prevalence of HPV infections in the oral and cervical mucosa of HIV-positive and HIV-negative women attending a sexual health clinic. Methods: One-hundred HIV-positive women and 100 HIV-negative women were recruited from a sexual health clinic in Sao Paulo, Brazil. All participants were given an oral and cervical examination. Cytologic samples were evaluated via HPV DNA test. Results: In oral samples, HPV DNA was observed in 11 women from the HIV-positive group and 2 from the HIV-negative group. High-risk HPV subtypes were prevalent in both groups and no difference between groups was detected. HPV DNA was detected in cervical scrapings from 41 HIV-positive women and 45 HIV-negative women (P = 0.67). No participants showed oral lesions, whereas 15 HIV-positive and 17 HIV-negative women presented with macroscopic genital lesions. Conclusion: HPV is detected more often in cervical scrapings than in oral samples. However, HPV oral shedding is more frequent in HIV-positive than in HIV-negative individuals. Concurrence of infection (high and low risk) was not observed in oral and cervical mucosa. (C) 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. (AU)

FAPESP's process: 08/00994-8 - Comparative analysis of the presence of Human papillomavirus in oral and cervix mucosa of HIV positive and negative women
Grantee:Marina Helena Cury Gallottini
Support Opportunities: Regular Research Grants