| Full text | |
| Author(s): |
Donadio Abduch, Maria Cristina
[1]
;
Salgo, Ivan
[2]
;
Tsang, Wendy
[3]
;
Campos Vieira, Marcelo Luiz
[1]
;
Cruz, Victoria
[1]
;
Lima, Marta
[1]
;
Tsutsui, Jeane Mike
[1]
;
Mor-Avi, Victor
[3]
;
Lang, Roberto M.
[3]
;
Mathias, Jr., Wilson
[1]
Total Authors: 10
|
| Affiliation: | [1] Univ Sao Paulo, Sch Med, Heart Inst InCor, Sao Paulo - Brazil
[2] Philips Healthcare, Andover, MA - USA
[3] Univ Chicago, Med Ctr, Chicago, IL 60637 - USA
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Arquivos Brasileiros de Cardiologia; v. 99, n. 3, p. 834-841, SEP 2012. |
| Web of Science Citations: | 6 |
| Abstract | |
BACKGROUND: The high and increasing prevalence of Dilated Cardiomyopathy (DCM) represents a serious public health problem. New technologies are being used aiming at more accurate diagnoses in order to improve therapeutic approach. In this scenario, speckle tracking echocardiography (STE) uses natural myocardial markers to analyze the systolic deformation of the left ventricle (LV). OBJECTIVE: To measure the longitudinal transmural global strain (GS) of the LV through STE in patients with severe DCM, comparing the results with normal individuals and with echocardiographic parameters established for the analysis of LV systolic function, validating the method in this population. METHODS: We studied 71 patients with severe DCM (53 ± 12 years, 72% men) and 20 controls (30 ± 8 years, 45% men). We obtained LV volumes and ejection fraction by two and three-dimensional echocardiography, Doppler parameters, tissue Doppler and GS was obtained by STE. RESULTS: Compared to controls, LV volumes were higher in the DCM group; however, LVEF and peak velocity of E wave were lower in the latter. The myocardial performance index was higher among patients. Myocardial velocities at the tissue Doppler (S', e', a') were significantly lower and E/e' ratio was higher in the DCM group. The GS was decreased in the DCM group (-5.5% ± 2.3%) when compared to controls (-14.0% ± 1.8%). CONCLUSION: In this study, GS was significantly lower in patients with severe DCM, bringing new perspectives for therapeutic approaches in this specific population. (AU) | |
| FAPESP's process: | 08/05723-2 - Cardiac torsion assessment through speckle-tracking echo in patients with dilated cardiomyopathy |
| Grantee: | Maria Cristina Donadio Abduch |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 04/07474-9 - Integrated study of ischemic and dilated cardiopathy: characterization and consolidation of ecocardiography in the evaluation of the coronary anatomy, myocardial function and perfusion |
| Grantee: | Wilson Mathias Júnior |
| Support Opportunities: | Research Projects - Thematic Grants |