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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Fibromyalgia and Sleep in Animal Models: A Current Overview and Future Directions

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Author(s):
Frange, Cristina [1] ; Hirotsu, Camila [1] ; Hachul, Helena [1] ; Araujo, Paula [1] ; Tufik, Sergio [1] ; Andersen, Monica L. [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Sao Paulo, Dept Psicobiol, BR-04024002 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Review article
Source: Current Pain and Headache Reports; v. 18, n. 8 AUG 2014.
Web of Science Citations: 4
Abstract

Sleep disorders are highly prevalent in patients with fibromyalgia (FM). Many of the daytime symptoms, such as chronic pain and fatigue, may be related to the non-restorative sleep patterns associated with the disease. Pain influences the sleep process and sleep disturbances decrease the pain threshold in a reciprocal framework. Thus, understanding the link between sleep and FM has become an important research topic in basic science. Therefore, in the current review we connect these topics and provide some insights into the cyclic relationship between sleep and pain, which has been addressed mainly in animal models. Additionally, we highlight the urgent need for sleep studies in FM animal models, which might improve the knowledge base and accelerate advances in this field. (AU)