| Grant number: | 17/25923-5 |
| Support Opportunities: | Regular Research Grants |
| Start date: | November 01, 2018 |
| End date: | October 31, 2020 |
| Field of knowledge: | Health Sciences - Physiotherapy and Occupational Therapy |
| Principal Investigator: | Luciano Bachmann |
| Grantee: | Luciano Bachmann |
| Host Institution: | Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil |
| City of the host institution: | Ribeirão Preto |
| Associated researchers: | Rinaldo Roberto de Jesus Guirro ; Theo Zeferino Pavan |
Abstract
Measure the tissue optical properties are fundamental for clinical phototherapy. Unknown the absorption and scattering coefficients or the optical penetration depth decreases the guarantee in processing the correct optical dosimetry of clinical systems. The solution is employ methodologies who measure the parameters accurately and preferentially in vivo and noninvasively. The objective is determining the optical properties of samples with high scattering properties in the near-infrared spectral region; including the optical sources spectroradiometry, diffuse reflectance and transmission spectroscopy; scattering and absorption coefficient determination from optical phantoms, optical-acoustic phantoms, enamel, dentine and skin. As sources we employ a tunable laser and halogens lamps. The numerical processing will be done with IAD (Inverse Adding-Doubling) algorithm. For expected results we highlight the system with one integrating sphere for in vivo and noninvasive application. To guarantee the validity of the in vivo measurements is necessary to have reference results for the scattering and absorption coefficients, for that we will measure phantoms, in vitro, with two integrating spheres and a laser as excitation source. (AU)
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