| Grant number: | 18/20200-8 |
| Support Opportunities: | Research Grants - Visiting Researcher Grant - International |
| Start date: | March 11, 2019 |
| End date: | March 17, 2019 |
| Field of knowledge: | Agronomical Sciences - Fishery Resources and Fishery Engineering - Aquaculture |
| Principal Investigator: | Ricardo Shohei Hattori |
| Grantee: | Ricardo Shohei Hattori |
| Visiting researcher: | Juan Ignacio Fernandino |
| Visiting researcher institution: | Universidad Nacional de San Martín (UNSAM) , Argentina |
| Host Institution: | APTA Regional. Agência Paulista de Tecnologia dos Agronegócios (APTA). Campinas , SP, Brazil |
| City of the host institution: | Campinas |
| Associated research grant: | 13/17612-9 - Genetic characterization, sex control, and germ cell transplantation in salmonids stocks from Estação Experimental de Salmonicultura de Campos do Jordão, AP.JP |
Abstract
Chronic exposures to thermal stress are able to affect the proliferation, differentiation and survival of germ cells. The complete depletion of these cells can result in fully sterile animals. At the genetic level, high temperatures can cause mutations and also induce epigenetic changes in the DNA, with the capacity to be transmitted to next generations, with implications on the survival and the capacity of fish to cope in environments more susceptible to climate changes, especially global warming. This study aims to clarify the regulatory mechanisms (genetic, molecular, and endocrine) involved in the maintenance and differentiation of germ cells in animals exposed to prolonged thermal stress using rainbow trout (Oncorhynchus mykiss) and medaka (Oryzias latipes) as experimental models. (AU)
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