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Microbiome of oral fluid of pigs and its relationship with fecal microbioma and detection of Salmonella enterica subsp. enterica


Several research groups studied swine microbiome of different samples, generally finding high frequency of Bacteriodetes e Firmicutes phyla, but no group studied the microbial composition of oral fluid until the present moment. Infection with Salmonella enterica subsp. enterica in pigs can cause negative impacts on farm productivity, and contamination of carcasses has been considered as one of the main vehicles of pathogens for humans, becoming a major public health problem. The collection of oral fluid is presented as an alternative for the search for antibodies and pathogens, with sensitivity similar to traditional methods and smaller impacts to animal welfare at the time of collection. Thus, the objective of this project will be to determine the microbioma of oral fluid of pigs and their relationships with the fecal microbioma composition and to verify the relationships between these compositions and the presence or absence of Salmonella enterica subsp. enterica. We expect that the sum of these results could support the use of oral fluid as a sample of choice for monitoring and sanitary surveys, favoring the collection of samples for the technician and reducing the impact on animal welfare, maintaining the diagnostic specificity and sensitivity. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ALVES, VINICIUS BUIATTE DE ANDRADE; CARVALHO, ENEAS; MADUREIRA, PALOMA ALONSO; MARINO, ELIZANGELA DOMENIS; VAZ, ANDREIA CRISTINA NAKASHIMA; VIDAL, ANA MARIA CENTOLA; RUIZ, VERA LETTICIE DE AZEVEDO. First isolation and whole-genome sequencing of a Shewanella algae strain from a swine farm in Brazil. BMC Microbiology, v. 20, n. 1, . (19/19473-2, 17/22184-7)

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