Study of the prevalence of neuropsychological deficits in patients recovered from COVID-19 associated with post-intensive care syndrome

• Grant number: 20/07957-2
• Support Opportunities: Regular Research Grants
• Start date: April 01, 2021
• End date: March 31, 2023
• Field of knowledge: Humanities - Psychology - Psychological Treatment and Prevention
• Principal Investigator: Antonio de Pádua Serafim
• Grantee: Antonio de Pádua Serafim
• Host Institution: Instituto de Psicologia (IP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Amanda Rafaella Abreu Soares ; Cristiana Castanho de Almeida Rocca ; Edgar Toschi Dias ; Ricardo Silva dos Santos Durães

Abstract

It is estimated that approximately one third or more of ICU survivors develop continuous and persistent cognitive impairment. As for patients with acute respiratory syndromes such as Covid-19, the prevalence of persistent cognitive impairment is even higher and can reach 78% in 1 year and 25% in 6 years. The literature has treated this phase of post-intensive care syndrome from English Post-intensive care syndrome (PICS), which describes, impairment of psychological health (emotional and cognitive) and physical function of patients who required ICU care. The aim of this study is to evaluate neuropsychological aspects in patients recovered from COVID-19. Method: Observational study that will use a digital platform containing a brief questionnaire of sociodemographic data and information on Covid-19 contamination and a neuropsychological battery with measures of attention, memory and executive functions, in addition to depressive and anxious aspects. It is intended to evaluate a sample of more than 500 participants for the composition of three groups: Light, Moderate and Serious Symptoms (treated in the ICU). The results of this study are expected to provide a cognitive overview of the sample to support the development of neuropsychological rehabilitation programs for patients with Covid-19 cognitive sequelae. (AU)