Development of films and hydrogels containing terpenes or derivative oligomers for active packaging and multifunctional medical devices applications

• Grant number: 22/02728-0
• Support Opportunities: Research Grants - Initial Project
• Start date: March 01, 2024
• End date: February 28, 2029
• Field of knowledge: Engineering - Chemical Engineering - Chemical Technology
• Principal Investigator: Roniérik Pioli Vieira
• Grantee: Roniérik Pioli Vieira
• Host Institution: Faculdade de Engenharia Química (FEQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated researchers: Lucia Helena Innocentini Mei ; Luís Marangoni Júnior ; Miguel Ângelo Parente Ribeiro Cerqueira ; Rosa Maria Vercelino Alves
• Associated scholarship(s): 25/05064-4 - Evaluation of Fruit Preservation in Poly(lactic acid)/Poly(butylene adipate-co-terephthalate) Blends Enhanced with Terpene-Derived Oligomers, BP.IC; 24/18832-7 - Experimental and simulation study of the synthesis of oligomers derived from terpenes, BP.MS; 24/13707-0 - Investigation of the use of polysorbates for the stabilization of oil-in-water emulsions containing terpenes/oligoterpenes, BP.IC; 24/00095-6 - Synthesis, characterization and processing of photo-crosslinkable hydrogels based on gelatin functionalized with norbornene groups and added with terpene oligomers, BP.DR

Abstract

This project includes two research fronts in multifunctional polymeric materials. The first of them will focus on packaging capable of enhancing food preservation, reducing losses and cross-contamination. In a connected way, the second front will address bioactive medical devices and their potential for mitigating public health problems related to microbial infections. The objective is to develop a technological platform involving the synthesis, characterization and processing of biopolymers containing terpenes or derived oligomers for such applications. Therefore, different synthetic routes and strategies for incorporating terpene bioactive compounds into polymeric matrices produced on a large scale will be investigated, obtaining films and photocrosslinkable hydrogels. The physical and functional properties related to the intended applications will be evaluated, in addition to a morphological and structural investigation. Additionally, preliminary studies on the processing of these materials will also be conducted to broaden the spectrum of potential applications. This project is expected to bring sustainable innovations in materials with improved performances to improve food security, health and population well-being. (AU)

Scientific publications

(11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SCHUTZ, GUILHERME FREY; GONCALVES, SAYENY DE AVILA; ALVES, ROSA MARIA VERCELINO; VIEIRA, RONIERIK PIOLI. A review of starch-based biocomposites reinforced with plant fibers. International Journal of Biological Macromolecules, v. 261, p. 20-pg., 2024-02-06. (22/02728-0)

VIANNA, THOMAS CORREA; GONCALVES, SAYENY DE AVILA; MARANGONI, LUIS; ALVES, ROSA MARIA VERCELINO; ANDRADE, VIVIAN TOMASCO; SATO, HELIA HARUMI; VIEIRA, RONIERIK PIOLI. Incorporation of Limonene Oligomers into Poly(itaconic acid)/Starch Blend Films for Antimicrobial and Antioxidant Packaging Applications. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 12, n. 23, p. 13-pg., 2024-04-19. (21/04043-2, 22/02728-0)

FERREIRA, CAROLINA CRUZ; SCHUTZ, GUILHERME FREY; TEIXEIRA, LUCAS NOVAES; MARTINEZ, ELIZABETH FERREIRA; VIEIRA, RONIERIK PIOLI; MEI, LUCIA HELENA INNOCENTINI. Synthesis and Characterization of Antibacterial Poly{2-[(methacryloyloxy)ethyl]trimethylammonium Chloride}/Chitosan Semi-Interpenetrating Networks for Papain Release. Macromolecular Bioscience, v. N/A, p. 11-pg., 2025-01-07. (22/02728-0)

SCHUTZ, GUILHERME FREY; ALVES, ROSA MARIA VERCELINO; DELARMELINA, CAMILA; DUARTE, MARTA CRISTINA TEIXEIRA. Limonene and its derived oligomer as bioactive additives in starch/coffee husks biocomposites for food packaging applications. International Journal of Biological Macromolecules, v. 260, p. 10-pg., 2024-01-18. (22/02728-0)

TOLEDO, GABRIEL FERREIRA; SCHUTZ, GUILHERME FREY; MARANGONI, LUIS; VIEIRA, RONIERIK PIOLI. Thermo-pressed blend films of poly(lactic acid)/poly(butylene adipate-co-terephthalate) co-terephthalate) with polylimonene for sustainable active food packaging. SUSTAINABLE MATERIALS AND TECHNOLOGIES, v. 41, p. 13-pg., 2024-08-24. (22/02728-0)

DE AVILA GONCALVES, SAYENY; DA FONSECA, JESSICA HELINE LOPES; DAVILA, MARCOS AKIRA; VIEIRA, RONIERIK PIOLI. Synthesis of thermally and pH-responsive poly(2-(dimethylamino)ethyl methacrylate)-based hydrogel reinforced with cellulose nanocrystals for sustained drug release. International Journal of Biological Macromolecules, v. 277, p. 13-pg., 2024-08-07. (22/02728-0)

GONCALVES, SAYENY DE AVILA; CECCATO, BRUNO TELLI; MORAES-LACERDA, THAIS; DE JESUS, MARCELO BISPO; DE LA TORRE, LUCIMARA GAZIOLA; VIEIRA, RONIERIK PIOLI. Synthesis of poly[2-(dimethylamino)ethyl methacrylate] grafting from cellulose nanocrystals for DNA complexation employing a 3D-twisted cross-sectional microchannel microfluidic device. International Journal of Biological Macromolecules, v. 305, p. 13-pg., 2025-05-01. (22/09246-1, 22/02728-0)

DE MELO, EDUARDA CHIABAI RODRIGUES; LONA, LILIANE MARIA FERRARESO; VIEIRA, RONIERIK PIOLI. Effects of filament extrusion temperature and 3D printing parameters on the structure and mechanical properties of poly(butylene adipate-co-terephthalate)/poly (lactic acid) blends. POLYMER ENGINEERING AND SCIENCE, v. N/A, p. 13-pg., 2024-12-30. (23/12419-8, 22/02728-0)

MAIA, GABRIELLA SIMON; MARANGONI JUNIOR, LUIS; VIEIRA, RONIERIK PIOLI. Tannic acid as a multifunctional additive in polysaccharide and protein-based films for enhanced food preservation: A comprehensive review. ADVANCES IN COLLOID AND INTERFACE SCIENCE, v. 339, p. 35-pg., 2025-05-01. (22/02728-0)

VIEIRA, RONIERIK PIOLI; SCHUTZ, GUILHERME FREY; PARMENTIER, LAURENS; VAN VLIERBERGHE, SANDRA. Effect of polylimonene on the release behavior and physico-chemical properties of photo-cross-linkable alginate-based hydrogels. SUSTAINABLE MATERIALS AND TECHNOLOGIES, v. 43, p. 14-pg., 2025-04-01. (22/03601-4, 22/02728-0)

DE MELO, EDUARDA CHIABAI RODRIGUES; LONA, LILIANE MARIA FERRARESO; VIEIRA, RONIERIK PIOLI. A Review on the Transformative Effects of Extrusion Parameters on Poly(Butylene adipate-co-terephthalate)/Poly(Lactic acid) Blends in 3D Printing. JOURNAL OF POLYMERS AND THE ENVIRONMENT, v. N/A, p. 29-pg., 2024-11-19. (23/12419-8, 22/02728-0)